1. Prefrontal Cortex Dysfunction (Cognitive Impairment) - Deepstash

1. Prefrontal Cortex Dysfunction (Cognitive Impairment)

The prefrontal cortex (PFC) is the part of your brain responsible for higher-order thinking—things like planning, decision-making, impulse control, and working memory. It’s like the CEO of your brain. When you’re under chronic stress, the PFC gets overwhelmed and starts to lose efficiency.

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Burnout is a prolonged stress response that overloads your brain’s systems, mainly involving three key areas: the prefrontal cortex, the amygdala, and the HPA axis (hypothalamic-pituitary-adrenal axis).

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